Severe Aplastic Anemia

Aplastic anemia consists of a group of diseases that are all linked with one another and have a negative impact on the blood cells and the bone marrow. In more severe cases of aplastic anemia, a bone marrow transplant or cord blood transplant could be necessary to increase the patient's chances of survival. However, in less severe cases, various treatments such as chemotherapy and medications could prevent the progression of aplastic anemia.

When someone is diagnosed with aplastic anemia, this means that their red blood cells, white blood cells and platelets are not producing in a healthy way. Red blood cells help to carry oxygen throughout the body, white blood cells help to fight infection and platelets are essential to clot the blood. However, for someone who is diagnosed with severe aplastic anemia, these cells are not functioning properly and therefore are causing risk to the overall health of the body.

Factors That Affect Transplant Outcomes

According to research, children are more likely to survive more severe cases of aplastic anemia than adults who are living with the disease. Researchers believe that this is because young adults and children typically respond better to transplants and they have a lower risk of developing graft-versus-host disease (GVHD). GVHD can commonly develop in those with severe aplastic anemia and it is a serious transplant complication that can oftentimes be life-threatening.

Many successful transplants occur in those who receive transplants from sibling donors. The success rate tends to be higher for these patients due to the fact that the closeness of the donor can have a strong impact on the outcome of the transplant.

However, when transplants go wrong for those living with severe anemic disorder, there could be other factors that come into play. For instance, the time between the diagnosis and the transplant can have a huge impact. When there is a longer time between the diagnosis and transplant, it can lead to a lower likelihood of patient survival since the severity of the disease was allowed to progress.
 
Study Results for Severe Aplastic Anemia

Several studies have been conducted on the causes and effects of severe aplastic anemia and research is still being done to find more effective treatments for the disease. Statistics show that a patient who receives a transplant from a sibling is 90 percent more likely to survive then one who receives a transplant from a donor outside their immediate family. A small study that was recently conducted showed the results of 50 patients who were treated with unrelated donor transplants. These patients reportedly had an overall 2-year survival rate of 57%.

Studies have also concluded that younger patients are able to fight the disease and are more receptive to treatments; however, this doesn't mean that younger patients aren't at risk when they are diagnosed with severe aplastic anemia.

Are you living with aplastic anemia and believe that it was wrongly caused? If so, please contact us today to speak with a trustworthy attorney who will evaluate your case and ensure that you receive the legal support and guidance you need and deserve.

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See Also:
    * What is Benzene
    * Treatment For Aplastic Anemia

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